In Situ Sterilizable Cell Culture Bioreactor

The most popular fermentation equipment and all kind of reactive fermentor machine including in situ sterilizable bioreactor and cell culture bioreactor,microbial fermentation,yogurt fermentation and so on.

Product Details


In situ sterilizable cell culture bioreactor


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Cell culture bioreactor details:

1. With Bench top, built-in peristaltic pumps

2. The interchangeable Vessels (10~50L)

3. Keeping Integrated Microprocessor controller

4. It is easy to operate, wash and make maintenance as it has the open frame structure and uses SUS316L plate.

5. Built-in type heater makes to be self-sterilization procedures.

6. The pH, DO, temperature and rotation speed of the agitator are measured and controlled by the integrated controller.

7. The temperature of the vessel is measured by the RTD (Pt-100) and controlled by the digital PID control algorithm.

8. 150W DC servo motor and the carbon-tungsten carbide mechanical seal protects agitation system from contamination

9. The rotation speed of the agitator is controlled from 50 rpm to 1,000 rpm.

 

Silver Double Limited manufactures various equipment related to bio-process for biotechnology, biochemical, pharmaceutical, agricultural, environment, life science industry. Especially, Our high performance of bioreactor system is suitable for both research and industrial bio-processing facilities.

 

In situ sterilizable fermentor system is designed for ease of use. The thermal heater is installed in the jacket of the fermentor vessel and not only the heater controls the temperature in the vessel but also it raises the temperature up to the sterilization temperature that it does not need the additional autoclave system. As this system is designed in the spirit of plant system that the result from this system can be directly applied to the mass production scheme. This system can be used to develop new products in the laboratory of the university or venture company. The result of the wonderful product can be applied in the SiDoLim pilot scale system directly which is manufactured by Silver Double Limited.

 

Agitation

Drive

DC motor, AC Gear motor, Top drive(mechanical seal driving)

Range

50~1000rpm ±1rpm

Impellers

Turbine impeller(SUS316L) Foam breaker (SUS316L)

Sensor

Magnetic Hall sensor

Control

Microprocessor based PID control

Materials&

Finish

Vessel

Using 316L stainless steel it is polished mechanically and electrically

Piping

316L stainless steel prevent contamination and is polished

O-rings/Gaskets

silicon material is used for the O-ring and the EPDM is used for gasket

Sterilization

Built-in heater makers the in-situ sterilization for   the vessel, head plate, filter, aeration pipe lines in 105℃~130℃temperature range automatically

Temperature

Range(℃)

From 3oC above the cooling water temperature to 80oC (accuracy±0.1 ℃)

Sensor

RTD(Pt-100)

Control

The built-in heater cartridge raises and cooling water pulling downs the water temperature and water pump circulates the water inside of the jacket

Aeration

Sparger

Ring sparger (SUS 316L)

Intel Filter

The cartridge type sterilizable pleated type 0.2um absolute filter specifications(option item)

Outer Filter

The same as internal filter specification(option item)

Control Range

Different vessel size and/or ordered specifications

Pressure Control

The back pressure is controlled manually or automatically

Control Unit

Panel

8.5"Graphic Color LCD, Membrane keypad

Communications

Memory stick,printer,computer with the RS-232C communications protocol

Controller Board

Microprocessor based integrated controller board is adopted to measure, control and display the fermentation system

Power Supply

220V 50/60Hz,Single phase

Data Storage

pH, DO, Pressure,Temperature and Agitation speed

 

Bioreactor cell cultureVessel


• The stainless steel (SUS316L) is used to prevent contamination and rust.

• The water jacket system is adopted for precise temperature control.

• The sight glass makes to monitor the status of the media.

• The spare ports are installed on the head plate that the auxiliary sensors can be installed.

• The sensor ports are installed in the circumferential direction on the lower side of the vessel.

 

Model

Total Vol.

(working Vol.)

Inner Dia.

Inner Heighta

Impeller Diameter

D/P

H:D

D

HP

SD-10

10L (7L)

190 mm

365 mm

80 mm

42%

2 :1

SD-15

15L (10L)

215 mm

430 mm

90 mm

42%

2 :1

SD-20

20L (14L)

235 mm

470 mm

95 mm

40%

2 :1

SD-30

30L (20L)

260 mm

555 mm

105 mm

40%

2 :1

SD-40

40L (30L)

295 mm

590 mm

120 mm

40%

2 :1

SD-50

50L(40L)

335 mm

635 mm

135 mm

40%

2 :1

 

 Our Services
1. Installation: We will send our engineer to help you with the installation and guide you with usage.

2. We will ensure the success of installation and commission.

3. Working life of main equipments: 15 years

4. Potential problem: Degradation of strain.
5. Solutions: Optimization and renew, we will supply the new strain freely in two years, then our engineer will provide techniques for optimization and renew.

6. Plant visit: We will arrange to visit one of similar lines we implemented in China and expect your coming!

 

Contact with me for more informations
sale  ( @ )   sentinaininc   .   com

 

 

 

 


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